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1. www.tsp2.orgTSP∙2

   www.tsp2.org

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   TSP2 is a program of AASHTO that provides information and resources on preserving highway infrastructure, including pavements and bridges. It also offers a clearinghouse for efficient and effective preservation measures and a waiver letter from FHWA.

   • Certification

     Introduction. Pavement preservation plays a critical role in...

     Web-Based Training Courses

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   • Standard Specifications

     2857 Jolly Road Okemos, MI 48864 Map. Hours of Operation. 8...

   • Contractor Employee

     Contractor Employee Certification. Company employee...

   • Members

     General Campaign Strategy. Campaign Outline. The outline...

   • CPAR Video

     Download the Video (Right-click Save As) – A five-minute...

2. tsp2bridge.pavementpreservation.orgTSP2 Bridge Preservation

   tsp2bridge.pavementpreservation.org

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   Oct 17, 2011 · TSP2 Bridge Preservation is a program that aims to prevent, delay or reduce deterioration of bridges or bridge elements. It provides information on different bridge preservation strategies, such as MWBPP, NEBPP, SEBPP and WBPP, and their invoices, receipts and FHWA's SP&R waiver letter.

3. tsp2bridge.pavementpreservation.org › midwest-mwbppMidwest (MWBPP) | TSP2 Bridge Preservation

   tsp2bridge.pavementpreservation.org › midwest-mwbpp

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   Midwest (MWBPP) | TSP2 Bridge Preservation. Constituents The Midwest Bridge Preservation Partnership (MWBPP) is comprised of representatives from regional state and local highway agencies, provincial transport agencies, industry, suppliers, consultants, and academia.

4. pubmed.ncbi.nlm.nih.gov › 11102746Thrombospondin 2, a matricellular protein with diverse ...

   pubmed.ncbi.nlm.nih.gov › 11102746

   Abstract. Thrombospondin (TSP) 2 is a close relative of TSP1 but differs in its temporal and spatial distribution in the mouse. This difference in expression undoubtedly reflects the marked disparity in the DNA sequences of the promoters in the genes encoding the two proteins.

   • Author: Paul Bornstein, Lucas C. Armstrong, Kurt D. Hankenson, Themis R. Kyriakides, Zhantao Yang

   • Publish Year: 2000

5. www.sciencedirect.com › science › articleTSP2 acts as a suppresser of cell invasion, migration and ...

   www.sciencedirect.com › science › article

   Sep 1, 2019 · Thrombospondin-2 (TSP2) is a matricellular protein that has been identified in human serum (Hanatani et al., 2014). A previous study reported that the upregulation of TSP2 induced by oxidative stress plays a significant role in angiogenesis dysfunction in diabetic bone marrow-derived angiogenic cells (Bae et al., 2013).

   • Author: Wei Pan, Xing-Yu Song, Qi-Bo Hu, Meng Zhang, Xiao-Heng Xu

   • Publish Year: 2019

6. www.sciencedirect.com › topics › medicine-andThrombospondin 2 - an overview | ScienceDirect Topics

   www.sciencedirect.com › topics › medicine-and

   Learn about thrombospondin 2 (TSP2), a matricellular protein that regulates collagen fibrillogenesis, angiogenesis, and inflammation. Find out the functions, interactions, and phenotypes of TSP2 and its knockout mice in various tissues and diseases.

7. People also ask

   How does tsp2 work at a distance?

   • Instead, emerging evidence supports a mode of action of TSP2 'at a distance', i.e. by modulating the activity and bioavailability of proteases and growth factors in the pericellular environment and, very likely, by interaction with cell-surface receptors.

   Thrombospondin 2, a matricellular protein with diverse functions

   pubmed.ncbi.nlm.nih.gov/11102746/

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   Is tsp2 overexpressing a signaling pathway-related gene?

   • A key finding of the current study revealed that overexpressing TSP2 could decrease the expression of the Notch signaling pathway-related genes, Hes-1, Hey-1 and JAG1. A recent study indicated that Hes-1 plays a critical role in a variety of cellular processes including differentiation, apoptosis, cell cycle and self-renewal ( Liu et al., 2015 ).

   TSP2 acts as a suppresser of cell invasion, migration and angiogenesis in

   www.sciencedirect.com/science/article/pii/S0006899319302513

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   Does tsp2 increase vascularity?

   • TSP2, like TSP1, is an inhibitor of angiogenesis. While there is a modest increase in vascularity in uninjured skin, vessel density is markedly increased in healing excisional skin wounds and in the foreign body capsule surrounding implanted biomaterials in TSP2-null mice.

   Thrombospondin 2 - an overview | ScienceDirect Topics

   www.sciencedirect.com/topics/medicine-and-dentistry/thrombospondin-2

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   Does tsp2 contribute to the structural integrity of connective tissue elements?

   • Despite the abnormalities in collagen fibrillogenesis, fragility of skin, and laxity of tendons and ligaments observed in the TSP2-null mouse, TSP2 does not appear to contribute directly to the structural integrity of connective tissue elements.

   Thrombospondin 2, a matricellular protein with diverse functions

   pubmed.ncbi.nlm.nih.gov/11102746/

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8. www.ncbi.nlm.nih.gov › pmc › articlesTSP1 and TSP2 have unique and overlapping roles in protecting ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Jun 1, 2019 · Thrombospondins (TSPs) are cell adhesion molecules that play an important role in the maintenance of hearing and afferent synaptic connections. Based on their reported function in restoring synaptic connections after stroke, we tested a potential role for TSP1 and TSP2 genes in repairing cochlear synapses following noise injury.