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  1. Jun 15, 2022 · Third-line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource-limited settings: ACTG A5288 strategy trial

  2. Sep 11, 2023 · CLT Charlotte, NC. left Gate 2 Asheville Rgnl - AVL. arrived at Gate E13 Charlotte/Douglas Intl - CLT. Monday 11-Sep-2023 07:33PM EDT. (7 minutes early) Monday 11-Sep-2023 08:54PM EDT. (on time) 1h 21m total travel time. Not your flight? AAL5288 flight schedule. Set Up Unlimited Flight Alerts & More.

  3. Jul 29, 2019 · We have proposed an algorithmic approach in A5288, which could serve as a compromise between individualised regimens and availability of only one or two third-line regimens. As treatment access has expanded, so has the number of people who might be appropriate for third-line ART.

    • Beatriz Grinsztejn, Michael D Hughes, Justin Ritz, Robert Salata, Peter Mugyenyi, Evelyn Hogg, Linda...
    • 2019
  4. Methods: A5288 was a phase 4, third-line ART strategy study done at 19 urban sites in ten countries that enrolled adult participants with confirmed plasma HIV-1 RNA (viral load) of 1000 copies per mL or more after more than 24 weeks of protease inhibitor-based second-line ART. The primary objective was to use antiretrovirals (raltegravir ...

    • Beatriz Grinsztejn, Michael D Hughes, Justin Ritz, Robert Salata, Peter Mugyenyi, Evelyn Hogg, Linda...
    • 2019
  5. Jul 16, 2012 · A5288 is a multi-step, open-label phase IV, prospective, interventional strategy study in resource-limited settings (RLS) for HIV-infected participants with triple-class experience or resistance (ie, to nucleoside reverse transcriptase inhibitors [NRTIs], non-NRTIs [NNRTIs], and protease inhibitors [PIs]) who are failing their current second ...

  6. Third-line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource-limited settings: ACTG A5288 strategy trial. J Int AIDS Soc. 2022 Jun;25 (6):e25905. doi: 10.1002/jia2.25905.

  7. Jul 1, 2019 · Methods: A5288 was a phase 4, third-line ART strategy study done at 19 urban sites in ten countries that enrolled adult participants with confirmed plasma HIV-1 RNA (viral load) of 1000 copies...