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  1. www.uniprot.org › uniprot › Q01740Q01740 - UniProt

    Jan 23, 2007 · Q01740 · FMO1_HUMAN. Protein. Flavin-containing monooxygenase 1. Gene. FMO1. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 532 (go to sequence) Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. Variant viewer. Feature viewer. Genomic coordinates. Publications. External links. History.

  2. Jan 14, 2013 · Details. This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. Dolphin C, Shephard EA, Povey S, Palmer CN, Ziegler DM, Ayesh R, Smith RL, Phillips IR: Cloning, primary sequence, and chromosomal mapping of a human flavin ...

  3. Apr 3, 2024 · fmo1_human,q01740 Reaction=NADPH + O2 + trimethylamine = H2O + NADP(+) + trimethylamine N-oxide; Xref= RHEA:31979 , CHEBI:15377 , CHEBI:15379 , CHEBI:15724 , CHEBI:57783 , CHEBI:58349 , CHEBI:58389 ; EC=1.14.13.148 ; Evidence={ ECO:0000250 UniProtKB: P36365 }.

  4. A flavin-containing monooxygenase 1 that is encoded in the genome of human. Protein Ontology. Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PMID: 32156684 ).

  5. This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with ...

  6. Description. Rabbit polyclonal to FMO1. Host species. Rabbit. Tested applications. Suitable for: IHC-P more details. Species reactivity. Reacts with: Human. Immunogen. Recombinant fragment corresponding to Human FMO1 aa 200-350. Database link: Q01740. Run BLAST with Run BLAST with. Positive control. IHC-P: Human liver and kidney tissue.

  7. Nov 23, 2023 · A8K248, B7Z3P4, Q01740, Q5QPT2, Q9UJC2 UniProtKB/TrEMBL B2RCG5 Related ENSP00000481732.1, ENST00000617670.6 Conserved Domains (1) summary pfam00743 Location: 2 → 532 FMO-like; Flavin-binding monooxygenase-like; NM_001282694.2 → NP_001269623.1 flavin-containing monooxygenase 1 isoform c. See identical proteins and their annotated locations ...