1. Including results for

    E2F4
    Search only for E28F4

  1. Ad

    related to: e2f4
  2. sigmaaldrich.com

    Molecular Cell E2F4 - E2F4 is essential

    Expertise on Every Level to Craft Science & Technology Solutions in Life Science. Essential for Normal Erythrocyte Maturation and Neonatal Viability

    Filtration · Applications & Technique · Advanced Structure Search · World-Class Expertise

Search Results

  1. www.nature.com › articles › s41467/019/10901-xE2F4 regulates transcriptional activation in mouse ... - Nature

    Jul 3, 2019 · E2F4 is a transcriptional repressor implicated in cell cycle arrest and whose repressive activity depends on its interaction with members of the RB family. Here we show that E2F4 is important...

    • Jenny Hsu, Julia Arand, Andrea Chaikovsky, Nancie A. Mooney, Janos Demeter, Caileen M. Brison, Roman...
    • 2019

  2. www.genecards.org › cgi-bin › carddispE2F4 Gene - GeneCards | E2F4 Protein | E2F4 Antibody

    Apr 2, 2024 · E2F4 (E2F Transcription Factor 4) is a Protein Coding gene. Diseases associated with E2F4 include Colorectal Cancer and Retinoblastoma. Among its related pathways are Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) and G0 and Early G1.

  3. People also ask

  4. en.wikipedia.org › wiki › E2F4E2F4 - Wikipedia

    Function. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds to all three of the tumor suppressor proteins ...

    • E2F4, E2F-4, E2F transcription factor 4

  5. www.nature.com › articles › s41568/019/0143-7The broken cycle: E2F dysfunction in cancer | Nature Reviews ...

    May 3, 2019 · E2F activity, as defined by expression of E2F target genes, is high in virtually all cancers, often owing to inactivation of its main binding partner and key regulator, RB (encoded by RB1 ),...

    • Lindsey N Kent, Gustavo Leone
    • 2019

  6. www.ncbi.nlm.nih.gov › pmc › articlesNovel functions for the transcription factor E2F4 in ...

    Oct 18, 2016 · Here we review the canonical functions of E2F4 and discuss recent evidence expanding the role of this transcription factor, with a focus on cell fate decisions in tissue homeostasis and regeneration. KEYWORDS: cancer, cell cycle, development, differentiation, E2F, E2F4, RB, regeneration, stem cells. Go to:

    • Jenny Hsu, Julien Sage
    • 10.1080/15384101.2016.1234551
    • 2016
    • Cell Cycle. 2016; 15(23): 3183-3190.

  7. www.nature.com › articles › s41598/022/16541-4E2F4 transcription factor is a prognostic biomarker related ...

    Jul 15, 2022 · E2F4 transcription factor is a prognostic biomarker related to immune infiltration of head and neck squamous cell carcinoma. Li Qi, Zihan Ren & Wei Li. Scientific Reports 12, Article number:...

  8. link.springer.com › article › 10Interplay between NRF1, E2F4 and MYC transcription factors ...

    Jul 25, 2018 · To identify common human NRF1, E2F4 and MYC target genes, we analyzed the Encyclopedia of DNA Elements (ENCODE) NRF1 ChIP-Seq data. By doing so, we identified 9253 common target genes with NRF1, E2F4 and MYC binding motifs.