Search Results

  1. www.candidagenome.org › cache › C_auris_B8441_genomeSnapshotCandida auris B8441 Genome Snapshot/Overview

    Genome Snapshot/Overview. This page provides information on the status of the C. auris B8441 genome. Data on this page are updated once a day. All the data displayed on this page are available in one or more files (Chromosomal Feature File; GO Annotations File; Candida Go Slim Annotations File) on the CGD Download Data page.

  2. www.nature.com › articles › s41467/018/07779-6Genomic insights into multidrug-resistance, mating and ...

    Dec 17, 2018 · The C. auris B8441 and B11221 genome assemblies were organized in 15 and 20 scaffolds, respectively, of which 7 scaffolds included most of the sequenced bases in both strains (Table 1).

    • José F. Muñoz, Lalitha Gade, Nancy A. Chow, Vladimir N. Loparev, Phalasy Juieng, Elizabeth L. Berkow...
    • 2018

  3. www.nature.com › articles › s41467/021/27545-5Forward and reverse genetic dissection of morphogenesis ...

    Dec 10, 2021 · For this mutant, we identified T-DNA sequence both in the intergenic space upstream of the B9J08_002954 ORF and in the intergenic region upstream of the B9J08_002667 ORF from the B8441 reference ...

  4. pubmed.ncbi.nlm.nih.gov › 34228535In Vitro Antifungal Resistance of Candida auris Isolates from ...

    Aug 17, 2021 · We sequenced the genomes of a subset of isolates and compared them to the C. auris B8441 reference strain. Of 400 C. auris isolates, 361 (90%) were resistant to at least one antifungal agent, 339 (94%) to fluconazole alone (MICs of ≥32 µg/ml), 19 (6%) to fluconazole and amphotericin B (MICs of ≥2 µg/ml), and 1 (0.3%) to amphotericin B alone.

    • Tsidiso G Maphanga, Serisha D Naicker, Stanford Kwenda, Jose F Muñoz, Erika van Schalkwyk, Jeannette...
    • 2021

  5. www.ncbi.nlm.nih.gov › pmc › articlesGenomic Diversity across Candida auris Clinical Isolates ...

    Jul 5, 2022 · High quality SNPs were annotated using snpEff (v4.3T) using the C. auris reference genome, B8441 (Cand_auris_B8441_V2). Genome-wide SNV-based phylogenetic analysis of the progenitor C. auris clinical isolates was conducted using the maximum likelihood method in RAxMLGUI (v2.0) using the variants generated above and included a total of 181,229 ...

    • 10.1128/mbio.00842-22
    • Jul-Aug 2022
    • mBio. 2022 Jul-Aug; 13(4): e00842-22.

  6. journals.plos.org › plospathogens › articleCandida auris: Epidemiology, biology, antifungal resistance ...

    Oct 22, 2020 · auris B8441 was sequenced by the CDC , and its sequence information and annotation is available on the Candida Genome Database (CGD) database (https://www.candidagenome.org). C. auris has 7 chromosomes, and the genome sizes of isolates range from 12.1 Mb to 12.7 Mb . Based on genomic and RNA-sequencing information, it is estimated that C.

  7. www.nature.com › articles › s41564/021/00915-xLncRNA DINOR is a virulence factor and global regulator of ...

    Jun 3, 2021 · The trimmed reads were aligned to the C. auris B8441 reference genome to identify the insertion site of each read. PB insertions at the same position but in the opposite orientation were counted ...